Hollender Lecture in Geriatric Psychiatry 2025-26A – Michael Rafii - 5/22/2026

Friday, May 22, 2026, 12:00 PM - 1:00 PM, Other, Nashville, TN

AMA PRA Category 1 Credits™ (1.00 hours), CE Credit for Psychologists (1.00 hours), Non-Physician Attendance (1.00 hours)

Psychiatry Grand Rounds is offered weekly on Friday from 12:00 to 1:00 pm in Luton Lecture Hall, Vanderbilt Psychiatric Hospital (VPH), room 1206. Format rotates between presentations by visiting speakers and Vanderbilt faculty on cutting edge science and discussion of challenging cases. After participating in this CME activity, participants should be able to describe and discuss uidelines, accepted best practice and evidence from recent research related to psychopathology, diagnosis, improving treatment selections, and educating patients about psychiatric illnesses, strategies for implementing new approaches or revising current approaches to managing patients with psychiatric disorders that result in a balanced approach to pathophysiologic, diagnostic, and treatment paradigms for patient care, and anticipated patient outcomes from revised or new management strategies.

Objective(s): 1 Describe and discuss guidelines, accepted best practice and evidence from recent research related to psychopathology, diagnosis, improving treatment selections, and educating patients about mental health illnesses. 2 Describe and discuss strategies for implementing new approaches or revising current approaches to managing patients with mental health disorders that result in a balanced approach to pathophysiologic, diagnostic, and treatment paradigms for patient care 3 Describe and discuss anticipated patient outcomes from revised or new management strategies
Location: Other
Specialties: Psychiatry and Behavioral Sciences

Faculty Disclosures:
Michael Rafii, MD (Advisor-AC Immune|Advisor-Aerska|Advisor-Alzheon|Advisor-Alnylam|Membership on Advisory Committees or Review Panels, Board Membership, etc.-Biohaven (Relationship has ended)|Advisor-Positrigo|Advisor-Recall Therapeutics|Advisor-Sumitomo|Grant or research support-Eisai|Advisor-Eli Lilly |Advisor-Ionis (Relationship has ended)|Advisor-Otsuka - 04/01/2026)

1. Describe and discuss guidelines, accepted best practice and evidence from recent research related to psychopathology, diagnosis, improving treatment selections, and educating patients about mental health illnesses.
2. Describe and discuss strategies for implementing new approaches or revising current approaches to managing patients with mental health disorders that result in a balanced approach to pathophysiologic, diagnostic, and treatment paradigms for patient care
3. Describe and discuss anticipated patient outcomes from revised or new management strategies

1. Explain why people with Down syndrome are at very high risk for developing Alzheimer’s disease, including the underlying genetic mechanisms.
2. Describe how Alzheimer’s disease unfolds biologically and clinically in individuals with Down syndrome, and how it compares to other forms of Alzheimer’s disease.
3. Discuss current and emerging clinical trials and therapeutic strategies aimed at preventing or slowing Alzheimer’s disease in adults with Down syndrome

Vanderbilt University Medical Center is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Vanderbilt University Medical Center designates this live activity for a maximum 1.00 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.